-Y, Y loss in leukemia
نویسنده
چکیده
Note Loss of the Y chromosome from individual metaphases is common in metaphase cells from both PHAstimulated lymphocytes and spontaneously dividing bone marrow cells. The frequency of Y loss is greater in older men, and the size of the 45,X,-Y cell population probably increases gradually with advancing age. (In females, a corollary loss of one X chromosome also occurs with advancing age.) This natural phenomenon challenges our ability to distinguish between a normal and a disease-associated 45,X,-Y clone.
منابع مشابه
O-7: Y Chromosome Microdeletions Are Not Associated with Spontaneous Recurrent Pregnancy Loss in A Sinhalese Population in Sri Lanka
Background: Many advances have been made in reproductive medicine yet the spontaneous loss of a pregnancy remains the most common complication of pregnancy. The aetiology of spontaneous recurrent pregnancy loss (RPL) is multifactorial. Y chromosome microdeletions are found in approximately 7% of men with low sperm counts and, compared to the general population, a higher frequency of spontaneous...
متن کاملMultiplex-Polymerase Chain Reaction for Detecting Microdeletions in The Azoospermia Factor Region of Y Chromosome in Iranian Couples with Non-Obstructive Infertility and Recurrent Pregnancy Loss
Objective Approximately 15 percent of couples are infertile. The male factor is responsible for approximately 50% of the cases. One of the main genetic factors playing a role in male infertility is Y chromosomal microdeletion within the proximal long arm of the Y chromosome (Yq11), named azoospermia factor (AZF) region. Recent studies have also demonstrated that there is a potential connection ...
متن کاملOptimization of Thermalisation Loss in the Quantum Dot Solar Cells using a Finite Element Method
As thermalisation loss is the dominant loss process in the quantum dot intermediate band solar cells (QD-IBSCs), it has been investigated and calculated for a QD-IBSC, where IB is created by embedding a stack of InAs(1-x) Nx QDs with a square pyramid shape in the intrinsic layer of the AlPySb(1-y) p-i-n structure. IB, which is an optically coupled but electrically isolated mini-band, divides th...
متن کاملبررسی ارتباط میان ریزحذفهای کامل کروموزوم Y و وقوع سقط مکرر در جمعیت ایرانی
Background: Recurrent pregnancy loss is a form of infertility with at least three consecutive pregnancy losses or more. Y chromosome microdeletions are a class of most likely genetic factors that occur in a special zone of Y chromosome which is named azoospermia factor region. The purpose of this study was to analyze the presence of Y chromosome complete microdeletions in male partner of couple...
متن کاملFractal Bandpass Filter Using Y-shaped Dual-Mode Resonator for C-Band Receiver (Research Note)
In this study, a fractal, Y-shaped dual-mode resonator bandpass filter (BPF) with input-output cross-coupling is introduced. A parallel-coupling feed structure with a cross coupling has been used to generate two transmission zeroes (TZs) near the lower and upper cutoff frequency that can effectively improve the passband edge selectivity. Also, a fractal shaped based on conventional diamond and ...
متن کاملویژگیهای روانسنجی پرسشنامه پاسخهای مقابله جوانان در بررسی افراد تحت درمان سرطان
AbstractObjectives: This study evaluated the psychometric properties of the Coping Responses Inventory for Youth (CRI-Y), assessing young adults undergoing treatment for cancer. The main goal of this study was to investigate the conceptual structure and reliability of this questionnaire in the Iranian cultural milieu (a kind of construct validity). In addition, the convergent and discriminati...
متن کامل